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BRUCE Antibody

25439

BRUCE Antibody

BRUCE Antibody (catalogue number 25439) is a rabbit-derived primary antibody validated for ELISA IHC, reactive with Human samples. It targets Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 (BIRC6): Anti-apoptotic protein known as inhibitor of apoptosis (IAP) which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Supplied as 100ul at ₪2,157.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
ELISA IHC
UniProt ID
Q9NR09
Gene
BIRC6
Target organism
Homo sapiens
Catalogue number
25439
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 (BIRC6) · Homo sapiens

Anti-apoptotic protein known as inhibitor of apoptosis (IAP) which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Unlike most IAPs, does not contain a RING domain and it is not a RING-type E3 ligase. Instead acts as a dual E2/E3 enzyme that combines ubiquitin conjugating (E2) and ubiquitin ligase (E3) activities in a single polypeptide. Ubiquitination is mediated by a non-canonical E1 ubiquitin activating enzyme UBA6.

Subcellular location: Golgi apparatus, trans-Golgi network membrane; Endosome; Cytoplasm, cytoskeleton, spindle pole; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Midbody, Midbody ring

Tissue specificity: Expressed in brain cancer cells

Sequence length: 4857 aa · 530269 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.