
25178
NOD6 Antibody
NOD6 Antibody (catalogue number 25178) is a rabbit-derived primary antibody validated for ELISA WB IHC, reactive with Hu Ms samples. It targets NACHT, LRR and PYD domains-containing protein 9 (NLRP9): As the sensor component of the NLRP9 inflammasome, plays a crucial role in innate immunity and inflammation. Supplied as 100ul at ₪2,157.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Hu Ms
- Applications
- ELISA WB IHC
- UniProt ID
- Q7RTR0
- Gene
- NLRP9
- Target organism
- Homo sapiens
- Catalogue number
- 25178
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: NACHT, LRR and PYD domains-containing protein 9 (NLRP9) · Homo sapiens
As the sensor component of the NLRP9 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens, including rotavirus, initiates the formation of the inflammasome polymeric complex, made of NLRP9, PYCARD and CASP1. Recruitment of proCASP1 to the inflammasome promotes its activation and CASP1-catalyzed IL1B and IL18 maturation and release in the extracellular milieu. The active cytokines stimulate inflammatory responses. Inflammasomes can also induce pyroptosis, an inflammatory form of programmed cell death.
Subcellular location: Cytoplasm; Inflammasome
Tissue specificity: Expressed in ileum intestinal epithelial cells. Not detected in peripheral blood mononuclear cells. Expressed in cerebral endothelial cells and, at much lower levels, in brain pericytes
Sequence length: 991 aa · 113312 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il