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RBBP8 Antibody

25120

RBBP8 Antibody

RBBP8 Antibody (catalogue number 25120) is a rabbit-derived primary antibody validated for ELISA WB IHC, reactive with Hu Ms Rt samples. It targets DNA endonuclease RBBP8 (RBBP8): Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in DNA-end resection, the first step of double-strand break (DSB) repair through the homologous recombination (HR) pathway. Supplied as 100ul at ₪2,157.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt
Applications
ELISA WB IHC
UniProt ID
Q99708
Gene
RBBP8
Target organism
Homo sapiens
Catalogue number
25120
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: DNA endonuclease RBBP8 (RBBP8) · Homo sapiens

Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in DNA-end resection, the first step of double-strand break (DSB) repair through the homologous recombination (HR) pathway. HR is restricted to S and G2 phases of the cell cycle and preferentially repairs DSBs resulting from replication fork collapse. Key determinant of DSB repair pathway choice, as it commits cells to HR by preventing classical non-homologous end-joining (NHEJ).

Subcellular location: Nucleus; Chromosome

Tissue specificity: Expressed in ER-positive breast cancer lines, but tends to be down-regulated ER-negative cells (at protein level)

Sequence length: 897 aa · 101942 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.