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MARCH8 Antibody

24788

MARCH8 Antibody

MARCH8 Antibody (catalogue number 24788) is a rabbit-derived primary antibody validated for ELISA WB ICC, reactive with Hu Ms Rt samples. It targets E3 ubiquitin-protein ligase MARCHF8 (MARCHF8): E3 ubiquitin-protein ligase that plays several important roles in innate immunity and adaptive immunity. Supplied as 100ul at ₪2,157.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt
Applications
ELISA WB ICC
UniProt ID
Q5T0T0
Gene
MARCHF8
Target organism
Homo sapiens
Catalogue number
24788
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: E3 ubiquitin-protein ligase MARCHF8 (MARCHF8) · Homo sapiens

E3 ubiquitin-protein ligase that plays several important roles in innate immunity and adaptive immunity. Mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. Possesses a very broad antiviral activity by specifically inactivating different viral fusion proteins. Targets and ubiquitinates cytoplasmic lysine residues of viral envelope glycoproteins with single transmembrane domains leading to their lysosomal degradation.

Subcellular location: Golgi apparatus membrane; Endoplasmic reticulum membrane; Cytoplasmic vesicle membrane; Lysosome membrane; Early endosome membrane

Tissue specificity: Broadly expressed. Present in immature dendritic cells (at protein level)

Sequence length: 291 aa · 32965 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.