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Spred2 Antibody

24774

Spred2 Antibody

Spred2 Antibody (catalogue number 24774) is a rabbit-derived primary antibody validated for ELISA WB, reactive with Human samples. It targets Sprouty-related, EVH1 domain-containing protein 2 (SPRED2): Negatively regulates Ras signaling pathways and downstream activation of MAP kinases. Supplied as 100ul at ₪2,157.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
ELISA WB
UniProt ID
Q7Z698
Gene
SPRED2
Target organism
Homo sapiens
Catalogue number
24774
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Sprouty-related, EVH1 domain-containing protein 2 (SPRED2) · Homo sapiens

Negatively regulates Ras signaling pathways and downstream activation of MAP kinases. Recruits and translocates NF1 to the cell membrane, thereby enabling NF1-dependent hydrolysis of active GTP-bound Ras to inactive GDP-bound Ras. Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells

Subcellular location: Cell membrane; Cytoplasmic vesicle, secretory vesicle membrane; Cytoplasm

Tissue specificity: Expressed in liver, skin, small intestine, salivary gland and prostate

Sequence length: 418 aa · 47558 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.