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PIKE Antibody

24242

PIKE Antibody

PIKE Antibody (catalogue number 24242) is a rabbit-derived primary antibody validated for ELISA WB IHC, reactive with Hu Ms samples. It targets Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP2): GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Supplied as 100ul at ₪2,157.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms
Applications
ELISA WB IHC
UniProt ID
Q99490
Gene
AGAP2
Target organism
Homo sapiens
Catalogue number
24242
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP2) · Homo sapiens

GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt.

Subcellular location: Cytoplasm; Nucleus

Tissue specificity: Isoform 1 is brain-specific. Isoform 2 is ubiquitously expressed, with highest levels in brain and heart

Sequence length: 1192 aa · 124591 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.