24212
TIRP Antibody
TIRP Antibody (catalogue number 24212) is a rabbit-derived primary antibody validated for ELISA WB ICC, reactive with Human samples. It targets TIR domain-containing adapter molecule 2 (TICAM2): Functions as a sorting adapter in different signaling pathways to facilitate downstream signaling leading to type I interferon induction. Supplied as 100ul at ₪2,157.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Human
- Applications
- ELISA WB ICC
- UniProt ID
- Q86XR7
- Gene
- TICAM2
- Target organism
- Homo sapiens
- Catalogue number
- 24212
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: TIR domain-containing adapter molecule 2 (TICAM2) · Homo sapiens
Functions as a sorting adapter in different signaling pathways to facilitate downstream signaling leading to type I interferon induction. In TLR4 signaling, physically bridges TLR4 and TICAM1 and functionally transmits signal to TICAM1 in early endosomes after endocytosis of TLR4. In TLR2 signaling, physically bridges TLR2 and MYD88 and is required for the TLR2-dependent movement of MYD88 to endosomes following ligand engagement. Involved in IL-18 signaling and is proposed to function as a sorting adapter for MYD88 in IL-18 signaling during adaptive immune response.
Subcellular location: Cytoplasm; Golgi apparatus; Cell membrane; Endoplasmic reticulum; Early endosome membrane; Late endosome membrane; Cell projection, phagocytic cup
Tissue specificity: Expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle, and pancreas Isoform 2 is ubiquitously expressed (at lower levels than isoform 1)
Sequence length: 235 aa · 26916 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il