
24022
DR4 Antibody
DR4 Antibody (catalogue number 24022) is a rabbit-derived primary antibody validated for ELISA WB ICC, reactive with Human samples. It targets Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A): Receptor for the cytotoxic ligand TNFSF10/TRAIL. Supplied as 100ul at ₪2,157.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Human
- Applications
- ELISA WB ICC
- UniProt ID
- O00220
- Gene
- TNFRSF10A
- Target organism
- Homo sapiens
- Catalogue number
- 24022
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) · Homo sapiens
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B
Subcellular location: Cell membrane; Membrane raft; Cytoplasm, cytosol
Tissue specificity: Widely expressed. High levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells
Sequence length: 468 aa · 50089 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il