
23068
ROCK1 antibody
ROCK1 antibody (catalogue number 23068) is a rabbit-derived primary antibody validated for WB IHC IF, reactive with Human samples. It targets Rho-associated protein kinase 1 (ROCK1): Protein kinase which is a key regulator of the actin cytoskeleton and cell polarity. Supplied as 100ul at ₪1,953.80; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Human
- Applications
- WB IHC IF
- UniProt ID
- Q13464
- Gene
- ROCK1
- Target organism
- Homo sapiens
- Catalogue number
- 23068
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: Rho-associated protein kinase 1 (ROCK1) · Homo sapiens
Protein kinase which is a key regulator of the actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress.
Subcellular location: Cytoplasm; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole; Golgi apparatus membrane; Cell projection, bleb; Cytoplasm, cytoskeleton; Cell membrane; Cell projection, lame
Tissue specificity: Detected in blood platelets
Sequence length: 1354 aa · 158175 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il