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Flightless I antibody

22392

Flightless I antibody

Flightless I antibody (catalogue number 22392) is a rabbit-derived primary antibody validated for WB IF, reactive with Human samples. It targets Protein flightless-1 homolog (FLII): Is a regulator of actin polymerization, required for proper myofibril organization and regulation of the length of sarcomeric thin filaments. Supplied as 100ul at ₪1,953.80; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
WB IF
UniProt ID
Q13045
Gene
FLII
Target organism
Homo sapiens
Catalogue number
22392
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Protein flightless-1 homolog (FLII) · Homo sapiens

Is a regulator of actin polymerization, required for proper myofibril organization and regulation of the length of sarcomeric thin filaments. It also plays a role in the assembly of cardiomyocyte cell adhesion complexes. Regulates cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling

Subcellular location: Nucleus; Cytoplasm, cytoskeleton; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Cell projection, podosome; Cell junction, focal adhesion

Tissue specificity: Strongest expression in skeletal muscle with high expression also in the heart and lung

Sequence length: 1269 aa · 144751 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.