Loading...
IL7 receptor D antibody

22228

IL7 receptor D antibody

IL7 receptor D antibody (catalogue number 22228) is a rabbit-derived primary antibody validated for Western blot, reactive with Human samples. It targets Interleukin-17 receptor D (IL17RD): Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. Supplied as 100ul at ₪1,953.80; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Western blot
UniProt ID
Q8NFM7
Gene
IL17RD
Target organism
Homo sapiens
Catalogue number
22228
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Interleukin-17 receptor D (IL17RD) · Homo sapiens

Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Might have a role in the early stages of fate specification of GnRH-secreting neurons. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells

Subcellular location: Golgi apparatus membrane; Cell membrane

Tissue specificity: Expressed in umbilical vein endothelial cells and in several highly vascularized tissues such as kidney, colon, skeletal muscle, heart and small intestine. Highly expressed in ductal epithelial cells of salivary glands, seminal vesicles and the collecting tubules of the kidney.

Sequence length: 739 aa · 82411 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.