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phosphate-regulating neutral endopeptidase antibody

22133

phosphate-regulating neutral endopeptidase antibody

phosphate-regulating neutral endopeptidase antibody (catalogue number 22133) is a rabbit-derived primary antibody validated for Western blot, reactive with Human samples. It targets Phosphate-regulating neutral endopeptidase PHEX (PHEX): Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity. Supplied as 100ul at ₪1,953.80; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Western blot
UniProt ID
P78562
Gene
PHEX
Target organism
Homo sapiens
Catalogue number
22133
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Phosphate-regulating neutral endopeptidase PHEX (PHEX) · Homo sapiens

Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity. Cleaves ASARM peptides between Ser and Glu or Asp residues. Regulates osteogenic cell differentiation and bone mineralization through the cleavage of the MEPE-derived ASARM peptide. Promotes dentin mineralization and renal phosphate reabsorption by cleaving DMP1- and MEPE-derived ASARM peptides. Inhibits the cleavage of MEPE by CTSB/cathepsin B thus preventing MEPE degradation

Subcellular location: Cell membrane

Tissue specificity: Specifically expressed in ovary. Expressed at low levels in kidney

Sequence length: 749 aa · 86474 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.