22105
EPS8 antibody
EPS8 antibody (catalogue number 22105) is a rabbit-derived primary antibody validated for WB IHC, reactive with Human samples. It targets Epidermal growth factor receptor kinase substrate 8 (EPS8): Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Supplied as 100ul at ₪1,953.80; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Human
- Applications
- WB IHC
- UniProt ID
- Q12929
- Gene
- EPS8
- Target organism
- Homo sapiens
- Catalogue number
- 22105
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: Epidermal growth factor receptor kinase substrate 8 (EPS8) · Homo sapiens
Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and actin bundling activities depending on the context.
Subcellular location: Cytoplasm, cell cortex; Cell projection, ruffle membrane; Cell projection, growth cone; Cell projection, stereocilium; Synapse, synaptosome
Tissue specificity: Expressed in all tissues analyzed, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Expressed in all epithelial and fibroblastic lines examined and in some, but not all, hematopoietic cells
Sequence length: 822 aa · 91882 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il