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Fibrillarin Antibody

21495

Fibrillarin Antibody

Fibrillarin Antibody (catalogue number 21495) is a rabbit-derived primary antibody validated for Western blot, reactive with Hu Ms Rt samples. It targets rRNA 2'-O-methyltransferase fibrillarin (FBL): S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt
Applications
Western blot
UniProt ID
P22087
Gene
FBL
Target organism
Homo sapiens
Catalogue number
21495
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: rRNA 2'-O-methyltransferase fibrillarin (FBL) · Homo sapiens

S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Probably catalyzes 2'-O-methylation of U6 snRNAs in box C/D RNP complexes. U6 snRNA 2'-O-methylation is required for mRNA splicing fidelity.

Subcellular location: Nucleus, nucleolus; Nucleus, nucleoplasm

Sequence length: 321 aa · 33784 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.