Loading...
Zap-70 (Ab-493) Antibody

21174

Zap-70 (Ab-493) Antibody

Zap-70 (Ab-493) Antibody (catalogue number 21174) is a rabbit-derived primary antibody validated for WB IHC, reactive with Hu Ms Rt samples. It targets Tyrosine-protein kinase ZAP-70 (ZAP70): Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt
Applications
WB IHC
UniProt ID
P43403
Gene
ZAP70
Target organism
Homo sapiens
Catalogue number
21174
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Tyrosine-protein kinase ZAP-70 (ZAP70) · Homo sapiens

Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates motility, adhesion and cytokine expression of mature T-cells, as well as thymocyte development. Also contributes to the development and activation of primary B-lymphocytes. When antigen presenting cells (APC) activate T-cell receptor (TCR), a serie of phosphorylations lead to the recruitment of ZAP70 to the phosphorylated TCR components CD3E and CD247/CD3Z through ITAM motif at the plasma membrane.

Subcellular location: Cytoplasm; Cell membrane

Tissue specificity: Expressed in T- and natural killer cells. Also present in early thymocytes and pro/pre B-cells

Sequence length: 619 aa · 69872 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.