Loading...
PAK1/PAK2/PAK3 (Ab-423/402/421) Antibody

21169

PAK1/PAK2/PAK3 (Ab-423/402/421) Antibody

PAK1/PAK2/PAK3 (Ab-423/402/421) Antibody (catalogue number 21169) is a rabbit-derived primary antibody validated for WB IHC IF, reactive with Hu Ms Rt samples. It targets Serine/threonine-protein kinase PAK 1 (PAK1): Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transp… Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt
Applications
WB IHC IF
UniProt ID
Q13153
Gene
PAK1
Target organism
Homo sapiens
Catalogue number
21169
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Serine/threonine-protein kinase PAK 1 (PAK1) · Homo sapiens

Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly phosphorylate BAD and protects cells against apoptosis. Activated by interaction with CDC42 and RAC1. Functions as a GTPase effector that links the Rho-related GTPases CDC42 and RAC1 to the JNK MAP kinase pathway. Phosphorylates and activates MAP2K1, and thereby mediates activation of downstream MAP kinases.

Subcellular location: Cytoplasm; Cell junction, focal adhesion; Cell projection, lamellipodium; Cell membrane; Cell projection, ruffle membrane; Cell projection, invadopodium; Nucleus, nucleoplasm; Chromosome; Cytoplasm, c

Tissue specificity: Overexpressed in gastric cancer cells and tissues (at protein level)

Sequence length: 545 aa · 60647 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.