
21153
MKK6 (Ab-207) Antibody
MKK6 (Ab-207) Antibody (catalogue number 21153) is a rabbit-derived primary antibody validated for WB IHC IF, reactive with Hu Ms Rt samples. It targets Dual specificity mitogen-activated protein kinase kinase 6 (MAP2K6): Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Hu Ms Rt
- Applications
- WB IHC IF
- UniProt ID
- P52564
- Gene
- MAP2K6
- Target organism
- Homo sapiens
- Catalogue number
- 21153
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: Dual specificity mitogen-activated protein kinase kinase 6 (MAP2K6) · Homo sapiens
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. With MAP3K3/MKK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 MAPK11, MAPK12, MAPK13 and MAPK14 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses. Especially, MAP2K3/MKK3 and MAP2K6/MKK6 are both essential for the activation of MAPK11 and MAPK13 induced by environmental stress, whereas MAP2K6/MKK6 is the major MAPK11 activator in response to TNF.
Subcellular location: Nucleus; Cytoplasm; Cytoplasm, cytoskeleton
Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas
Sequence length: 334 aa · 37492 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il