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p21Cip1 (Ab45) Antibody

21149

p21Cip1 (Ab45) Antibody

p21Cip1 (Ab45) Antibody (catalogue number 21149) is a rabbit-derived primary antibody validated for Western blot, reactive with Human samples. It targets Cyclin-dependent kinase inhibitor 1 (CDKN1A): Plays an important role in controlling cell cycle progression and DNA damage-induced G2 arrest. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Western blot
UniProt ID
P38936
Gene
CDKN1A
Target organism
Homo sapiens
Catalogue number
21149
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Cyclin-dependent kinase inhibitor 1 (CDKN1A) · Homo sapiens

Plays an important role in controlling cell cycle progression and DNA damage-induced G2 arrest. Involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Also involved in p53-independent DNA damage-induced G2 arrest mediated by CREB3L1 in astrocytes and osteoblasts. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1.

Subcellular location: Cytoplasm; Nucleus

Tissue specificity: Expressed in all adult tissues, with 5-fold lower levels observed in the brain

Sequence length: 164 aa · 18119 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.