14314
IGF1R (Phospho-Tyr1135/1136)/Insulin Receptor β (Phospho-Tyr1150/1151) Rabbit mAb
IGF1R (Phospho-Tyr1135/1136)/Insulin Receptor β (Phospho-Tyr1150/1151) Rabbit mAb (catalogue number 14314) is a recombinant rabbit rabbit-derived recombinant phospho rabbit antibody validated for Western blot, reactive with Human, Mouse, Rat samples. It targets Insulin receptor (INSR): Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Recombinant Rabbit Rabbit
- Reactivity
- Human, Mouse, Rat
- Applications
- Western blot
- UniProt ID
- P06213
- Gene
- INSR
- Target organism
- Homo sapiens
- Catalogue number
- 14314
- Brand
- LABO Scientific
- Storage
- Store at -20°C /1 year
Target background
Target: Insulin receptor (INSR) · Homo sapiens
Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated proteins serve as docking proteins for other signaling proteins that contain Src-homology-2 domains (SH2 domain) that specifically recognize different phosphotyrosine residues, including the p85 regulatory subunit of PI3K and SHP2.
Subcellular location: Cell membrane; Late endosome; Lysosome
Tissue specificity: Isoform Long and isoform Short are predominantly expressed in tissue targets of insulin metabolic effects: liver, adipose tissue and skeletal muscle but are also expressed in the peripheral nerve, kidney, pulmonary alveoli, pancreatic acini, placenta vascular endothelium, fibroblasts, monocytes, gra…
Sequence length: 1382 aa · 156333 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C /1 year
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il