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CBL (Phospho-Tyr774) Rabbit mAb

14270

CBL (Phospho-Tyr774) Rabbit mAb

CBL (Phospho-Tyr774) Rabbit mAb (catalogue number 14270) is a recombinant rabbit rabbit-derived recombinant phospho rabbit antibody validated for Western blot, Immunohistochemistry, reactive with Human samples. It targets E3 ubiquitin-protein ligase CBL (CBL): E3 ubiquitin-protein ligase that acts as a negative regulator of many signaling pathways by mediating ubiquitination of cell surface receptors. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Recombinant Phospho Rabbit AntibodyHostRecombinant Rabbit Rabbit
Host / source
Recombinant Rabbit Rabbit
Reactivity
Human
Applications
Western blot Immunohistochemistry
UniProt ID
P22681
Gene
CBL
Target organism
Homo sapiens
Catalogue number
14270
Brand
LABO Scientific
Storage
Store at -20°C. Avoid freeze/thaw cycles.

Target background

Target: E3 ubiquitin-protein ligase CBL (CBL) · Homo sapiens

E3 ubiquitin-protein ligase that acts as a negative regulator of many signaling pathways by mediating ubiquitination of cell surface receptors. Accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including KIT, FLT1, FGFR1, FGFR2, PDGFRA, PDGFRB, CSF1R, EPHA8 and KDR and mediates their ubiquitination to terminate signaling. Recognizes membrane-bound HCK, SRC and other kinases of the SRC family and mediates their ubiquitination and degradation.

Subcellular location: Cytoplasm; Cell membrane; Cell projection, cilium; Golgi apparatus

Sequence length: 906 aa · 99633 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.