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Smad2 (Phospho-Ser250) Rabbit mAb

14211

Smad2 (Phospho-Ser250) Rabbit mAb

Smad2 (Phospho-Ser250) Rabbit mAb (catalogue number 14211) is a recombinant rabbit-derived kdko validated recombinant monoclonal antibody validated for WB FC, reactive with Human Mouse Rat samples. It targets SMAD family member 2 (SMAD2): Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

KDKO Validated Recombinant Monoclonal AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Applications
WB FC
UniProt ID
Q15796
Gene
SMAD2
Target organism
Homo sapiens
Catalogue number
14211
Brand
LABO Scientific
Storage
Store at -20°C. Avoid freeze/thaw cycles.

Target background

Target: SMAD family member 2 (SMAD2) · Homo sapiens

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. Promotes TGFB1-mediated transcription of odontoblastic differentiation genes in dental papilla cells. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

Subcellular location: Cytoplasm; Nucleus

Tissue specificity: Expressed at high levels in skeletal muscle, endothelial cells, heart and placenta

Sequence length: 467 aa · 52306 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.