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YAP1 (Phospho-Ser127) Rabbit mAb

14199

YAP1 (Phospho-Ser127) Rabbit mAb

YAP1 (Phospho-Ser127) Rabbit mAb (catalogue number 14199) is a recombinant rabbit-derived primary antibody validated for WB IHC, reactive with Human Mouse Rat samples. It targets Transcriptional coactivator YAP1 (YAP1): Transcriptional regulator with dual roles as a coactivator and corepressor. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Applications
WB IHC
UniProt ID
P46937
Gene
YAP1
Target organism
Homo sapiens
Catalogue number
14199
Brand
LABO Scientific
Storage
Store at -20°C. Avoid freeze/thaw cycles.

Target background

Target: Transcriptional coactivator YAP1 (YAP1) · Homo sapiens

Transcriptional regulator with dual roles as a coactivator and corepressor. Critical downstream regulatory target in the Hippo signaling pathway, crucial for organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The Hippo signaling pathway core involves a kinase cascade featuring STK3/MST2 and STK4/MST1, along with its regulatory partner SAV1, which phosphorylates and activates LATS1/2 in complex with their regulatory protein, MOB1. This activation leads to the phosphorylation and inactivation of the YAP1 oncoprotein and WWTR1/TAZ.

Subcellular location: Cytoplasm; Nucleus; Cell junction, tight junction; Cell membrane

Tissue specificity: Increased expression seen in some liver and prostate cancers. Isoforms lacking the transactivation domain found in striatal neurons of patients with Huntington disease (at protein level)

Sequence length: 504 aa · 54462 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.