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COP1 (phospho Ser387) Polyclonal Antibody

13956

COP1 (phospho Ser387) Polyclonal Antibody

COP1 (phospho Ser387) Polyclonal Antibody (catalogue number 13956) is a rabbit-derived primary antibody validated for Western blot, ELISA, reactive with Human, Mouse samples. It targets E3 ubiquitin-protein ligase COP1 (COP1): E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse
Applications
Western blot ELISA
UniProt ID
Q8NHY2
Gene
COP1
Target organism
Homo sapiens
Catalogue number
13956
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: E3 ubiquitin-protein ligase COP1 (COP1) · Homo sapiens

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in JUN ubiquitination and degradation. Directly involved in p53 (TP53) ubiquitination and degradation, thereby abolishing p53-dependent transcription and apoptosis. Ubiquitinates p53 independently of MDM2 or RCHY1.

Subcellular location: Nucleus speckle; Cytoplasm

Tissue specificity: Ubiquitously expressed at low level. Expressed at higher level in testis, placenta, skeletal muscle and heart

Sequence length: 731 aa · 80474 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.