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FAS (phospho Tyr291) Polyclonal Antibody

13871

FAS (phospho Tyr291) Polyclonal Antibody

FAS (phospho Tyr291) Polyclonal Antibody (catalogue number 13871) is a rabbit-derived primary antibody validated for IF/ICC, ELISA, reactive with Human samples. It targets Tumor necrosis factor receptor superfamily member 6 (FAS): Receptor for TNFSF6/FASLG. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
IF/ICC ELISA
UniProt ID
P25445
Gene
FAS
Target organism
Homo sapiens
Catalogue number
13871
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Tumor necrosis factor receptor superfamily member 6 (FAS) · Homo sapiens

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro)

Subcellular location: Cell membrane; Membrane raft

Tissue specificity: Isoform 1 and isoform 6 are expressed at equal levels in resting peripheral blood mononuclear cells. After activation there is an increase in isoform 1 and decrease in the levels of isoform 6

Sequence length: 335 aa · 37732 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.