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HER2 (Phospho-Tyr1139) Polyclonal Antibody

13826

HER2 (Phospho-Tyr1139) Polyclonal Antibody

HER2 (Phospho-Tyr1139) Polyclonal Antibody (catalogue number 13826) is a rabbit-derived primary antibody validated for IHC-p, IF(paraffin section), Western blot, reactive with Human, Mouse, Rat samples. It targets Receptor tyrosine-protein kinase erbB-2 (ERBB2): Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC-p IF(paraffin section) Western blot
UniProt ID
P04626
Gene
ERBB2
Target organism
Homo sapiens
Catalogue number
13826
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Receptor tyrosine-protein kinase erbB-2 (ERBB2) · Homo sapiens

Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane.

Subcellular location: Cell membrane; Cell projection, ruffle membrane

Tissue specificity: Expressed in a variety of tumor tissues including primary breast tumors and tumors from small bowel, esophagus, kidney and mouth

Sequence length: 1255 aa · 137910 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.