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MITF (phospho Ser180) Polyclonal Antibody

13708

MITF (phospho Ser180) Polyclonal Antibody

MITF (phospho Ser180) Polyclonal Antibody (catalogue number 13708) is a rabbit-derived primary antibody validated for Western blot, IHC-p, IF(paraffin section), ELISA, reactive with Human, Mouse, Monkey samples. It targets Microphthalmia-associated transcription factor (MITF): Transcription factor that acts as a master regulator of melanocyte survival and differentiation as well as melanosome biogenesis. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Monkey
Applications
Western blot IHC-p IF(paraffin section) ELISA
UniProt ID
O75030
Gene
MITF
Target organism
Homo sapiens
Catalogue number
13708
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Microphthalmia-associated transcription factor (MITF) · Homo sapiens

Transcription factor that acts as a master regulator of melanocyte survival and differentiation as well as melanosome biogenesis. Binds to M-boxes (5'-TCATGTG-3') and symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoter of pigmentation genes, such as tyrosinase (TYR). Involved in the cellular response to amino acid availability by acting downstream of MTOR: in the presence of nutrients, MITF phosphorylation by MTOR promotes its inactivation. Upon starvation or lysosomal stress, inhibition of MTOR induces MITF dephosphorylation, resulting in transcription factor activity.

Subcellular location: Nucleus; Cytoplasm; Lysosome membrane

Tissue specificity: Expressed in melanocytes (at protein level)

Sequence length: 526 aa · 58795 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.