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PLB (phospho Ser16/T17) Polyclonal Antibody

13608

PLB (phospho Ser16/T17) Polyclonal Antibody

PLB (phospho Ser16/T17) Polyclonal Antibody (catalogue number 13608) is a rabbit-derived primary antibody validated for IF/ICC, ELISA, reactive with Human, Mouse, Rat samples. It targets Phospholamban (PLN): Reversibly inhibits the activity of ATP2A2/SERCA2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IF/ICC ELISA
UniProt ID
P26678
Gene
PLN
Target organism
Homo sapiens
Catalogue number
13608
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Phospholamban (PLN) · Homo sapiens

Reversibly inhibits the activity of ATP2A2/SERCA2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Binds preferentially to the ATP-bound E1 conformational form of ATP2A2 which predominates at low Ca(2+) concentrations during the diastolic phase of the cardiac cycle. Inhibits ATP2A2 Ca(2+) affinity by disrupting its allosteric activation by ATP. Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2.

Subcellular location: Endoplasmic reticulum membrane; Sarcoplasmic reticulum membrane; Mitochondrion membrane; Membrane

Tissue specificity: Heart muscle (at protein level)

Sequence length: 52 aa · 6109 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.