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Tensin-2 (phospho Tyr483) Polyclonal Antibody

13486

Tensin-2 (phospho Tyr483) Polyclonal Antibody

Tensin-2 (phospho Tyr483) Polyclonal Antibody (catalogue number 13486) is a rabbit-derived primary antibody validated for Western blot, ELISA, reactive with Human, Mouse samples. It targets Tensin-2 (TNS2): Tyrosine-protein phosphatase which regulates cell motility, proliferation and muscle-response to insulin. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse
Applications
Western blot ELISA
UniProt ID
Q63HR2
Gene
TNS2
Target organism
Homo sapiens
Catalogue number
13486
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Tensin-2 (TNS2) · Homo sapiens

Tyrosine-protein phosphatase which regulates cell motility, proliferation and muscle-response to insulin. Phosphatase activity is mediated by binding to phosphatidylinositol-3,4,5-triphosphate (PtdIns(3,4,5)P3) via the SH2 domain. In muscles and under catabolic conditions, dephosphorylates IRS1 leading to its degradation and muscle atrophy. Negatively regulates PI3K-AKT pathway activation. Dephosphorylates nephrin NPHS1 in podocytes which regulates activity of the mTORC1 complex.

Subcellular location: Cell junction, focal adhesion; Cell membrane; Cytoplasm

Tissue specificity: Detected in heart, kidney, brain, thymus, spleen, liver, placenta, lung, skeletal muscle and small intestine

Sequence length: 1409 aa · 152580 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.