Loading...
Topo IIα (phospho Ser1106) Polyclonal Antibody

13474

Topo IIα (phospho Ser1106) Polyclonal Antibody

Topo IIα (phospho Ser1106) Polyclonal Antibody (catalogue number 13474) is a rabbit-derived primary antibody validated for Western blot, IHC-p, IF(paraffin section), ELISA, reactive with Human samples. It targets DNA topoisomerase 2-alpha (TOP2A): Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Western blot IHC-p IF(paraffin section) ELISA
UniProt ID
P11388
Gene
TOP2A
Target organism
Homo sapiens
Catalogue number
13474
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: DNA topoisomerase 2-alpha (TOP2A) · Homo sapiens

Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. May play a role in regulating the period length of BMAL1 transcriptional oscillation

Subcellular location: Cytoplasm; Nucleus, nucleoplasm; Nucleus; Nucleus, nucleolus

Tissue specificity: Expressed in the tonsil, spleen, lymph node, thymus, skin, pancreas, testis, colon, kidney, liver, brain and lung. Also found in high-grade lymphomas, squamous cell lung tumors and seminomas

Sequence length: 1531 aa · 174385 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.