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VHL (Phospho-Ser68) Antibody

12654

VHL (Phospho-Ser68) Antibody

VHL (Phospho-Ser68) Antibody (catalogue number 12654) is a rabbit-derived primary antibody validated for Immunohistochemistry, Immunofluorescence, reactive with Hu Ms Rt samples. It targets von Hippel-Lindau disease tumor suppressor (VHL): Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt
Applications
Immunohistochemistry Immunofluorescence
UniProt ID
P40337
Gene
VHL
Target organism
Homo sapiens
Catalogue number
12654
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: von Hippel-Lindau disease tumor suppressor (VHL) · Homo sapiens

Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2. Acts as a negative regulator of mTORC1 by promoting ubiquitination and degradation of RPTOR

Subcellular location: Cytoplasm; Cell membrane; Endoplasmic reticulum; Nucleus

Tissue specificity: Expressed in the adult and fetal brain and kidney

Sequence length: 213 aa · 24153 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.