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FKHRL1 (Phospho-Ser644) Antibody

12476

FKHRL1 (Phospho-Ser644) Antibody

FKHRL1 (Phospho-Ser644) Antibody (catalogue number 12476) is a rabbit-derived primary antibody validated for Western blot, reactive with Hu Ms Rt samples. It targets Forkhead box protein O3 (FOXO3): Transcriptional activator that recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' and regulates different processes, such as apoptosis and autophagy. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms Rt
Applications
Western blot
UniProt ID
O43524
Gene
FOXO3
Target organism
Homo sapiens
Catalogue number
12476
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Forkhead box protein O3 (FOXO3) · Homo sapiens

Transcriptional activator that recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' and regulates different processes, such as apoptosis and autophagy. Acts as a positive regulator of autophagy in skeletal muscle: in starved cells, enters the nucleus following dephosphorylation and binds the promoters of autophagy genes, such as GABARAP1L, MAP1LC3B and ATG12, thereby activating their expression, resulting in proteolysis of skeletal muscle proteins. Triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress.

Subcellular location: Cytoplasm, cytosol; Nucleus; Mitochondrion matrix; Mitochondrion outer membrane

Tissue specificity: Ubiquitous

Sequence length: 673 aa · 71277 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.