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PRC1(Phospho-Thr481)Polyclonal Antibody

12399

PRC1(Phospho-Thr481)Polyclonal Antibody

PRC1(Phospho-Thr481)Polyclonal Antibody (catalogue number 12399) is a rabbit-derived primary antibody validated for Western blot, reactive with Human samples. It targets Protein regulator of cytokinesis 1 (PRC1): Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Western blot
UniProt ID
O43663
Gene
PRC1
Target organism
Homo sapiens
Catalogue number
12399
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Protein regulator of cytokinesis 1 (PRC1) · Homo sapiens

Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression

Subcellular location: Nucleus; Cytoplasm; Cytoplasm, cytoskeleton, spindle pole; Midbody; Chromosome

Tissue specificity: Overexpressed in bladder cancer cells

Sequence length: 620 aa · 71607 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.