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Phospho-GRK 2 (S685) Polyclonal Antibody

12397

Phospho-GRK 2 (S685) Polyclonal Antibody

Phospho-GRK 2 (S685) Polyclonal Antibody (catalogue number 12397) is a primary antibody validated for WB ELISA, reactive with Hu Ms Rt samples. It targets G protein-coupled receptor kinase 2 (GRK2): Specifically phosphorylates the activated forms of G protein-coupled receptors. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary Antibody
Reactivity
Hu Ms Rt
Applications
WB ELISA
UniProt ID
P25098
Gene
GRK2
Target organism
Homo sapiens
Catalogue number
12397
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: G protein-coupled receptor kinase 2 (GRK2) · Homo sapiens

Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor internalization, and signaling events leading to their desensitization. Phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Phosphorylates catecholamine-activated ADRB2 to regulate physiological cardiomyocyte contraction rate responses.

Subcellular location: Cytoplasm; Cell membrane; Cell projection, cilium membrane; Postsynapse; Presynapse

Tissue specificity: Expressed in peripheral blood leukocytes

Sequence length: 689 aa · 79574 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.