Loading...
TIRAP (Phospho-Tyr86) Polyclonal Antibody

12384

TIRAP (Phospho-Tyr86) Polyclonal Antibody

TIRAP (Phospho-Tyr86) Polyclonal Antibody (catalogue number 12384) is a rabbit-derived primary antibody validated for WB IHC ELISA, reactive with Hu Ms samples. It targets Toll/interleukin-1 receptor domain-containing adapter protein (TIRAP): Adapter involved in TLR2, TLR4 and RAGE signaling pathways in the innate immune response. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms
Applications
WB IHC ELISA
UniProt ID
P58753
Gene
TIRAP
Target organism
Homo sapiens
Catalogue number
12384
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Toll/interleukin-1 receptor domain-containing adapter protein (TIRAP) · Homo sapiens

Adapter involved in TLR2, TLR4 and RAGE signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF (TNF) and interleukin-6 (IL6)

Subcellular location: Cytoplasm; Cell membrane; Membrane

Tissue specificity: Highly expressed in liver, kidney, spleen, skeletal muscle and heart. Also detected in peripheral blood leukocytes, lung, placenta, small intestine, thymus, colon and brain

Sequence length: 221 aa · 23883 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.