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TRF1 (Phospho-Ser219) Polyclonal Antibody

12251

TRF1 (Phospho-Ser219) Polyclonal Antibody

TRF1 (Phospho-Ser219) Polyclonal Antibody (catalogue number 12251) is a rabbit-derived primary antibody validated for WB ELISA, reactive with Hu Ms samples. It targets Telomeric repeat-binding factor 1 (TERF1): Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Hu Ms
Applications
WB ELISA
UniProt ID
P54274
Gene
TERF1
Target organism
Homo sapiens
Catalogue number
12251
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Telomeric repeat-binding factor 1 (TERF1) · Homo sapiens

Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways

Subcellular location: Nucleus; Cytoplasm, cytoskeleton, spindle; Chromosome, telomere

Tissue specificity: Highly expressed and ubiquitous. Isoform Pin2 predominates

Sequence length: 439 aa · 50246 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.