
12215
p70 S6 kinase α (Phospho-Ser447) Polyclonal Antibody
p70 S6 kinase α (Phospho-Ser447) Polyclonal Antibody (catalogue number 12215) is a rabbit-derived primary antibody validated for WB IHC ELISA, reactive with Hu Ms Rt samples. It targets Ribosomal protein S6 kinase beta-1 (RPS6KB1): Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Hu Ms Rt
- Applications
- WB IHC ELISA
- UniProt ID
- P23443
- Gene
- RPS6KB1
- Target organism
- Homo sapiens
- Catalogue number
- 12215
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: Ribosomal protein S6 kinase beta-1 (RPS6KB1) · Homo sapiens
Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex.
Subcellular location: Synapse, synaptosome; Mitochondrion outer membrane; Mitochondrion
Tissue specificity: Widely expressed
Sequence length: 525 aa · 59140 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il