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Shc1 (Phospho-Tyr427) Antibody

11317

Shc1 (Phospho-Tyr427) Antibody

Shc1 (Phospho-Tyr427) Antibody (catalogue number 11317) is a rabbit-derived primary antibody validated for WB IHC IF, reactive with Human samples. It targets SHC-transforming protein 1 (SHC1): Signaling adapter that couples activated growth factor receptors to signaling pathways. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
WB IHC IF
UniProt ID
P29353
Gene
SHC1
Target organism
Homo sapiens
Catalogue number
11317
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: SHC-transforming protein 1 (SHC1) · Homo sapiens

Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems.

Subcellular location: Cytoplasm; Cell junction, focal adhesion

Tissue specificity: Widely expressed. Expressed in neural stem cells but absent in mature neurons

Sequence length: 583 aa · 62822 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.