
11190
APP (Phospho-Thr668) Antibody
APP (Phospho-Thr668) Antibody (catalogue number 11190) is a rabbit-derived primary antibody validated for Western blot, reactive with Hu Ms Rt samples. It targets Amyloid-beta precursor protein (APP): Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Hu Ms Rt
- Applications
- Western blot
- UniProt ID
- P05067
- Gene
- APP
- Target organism
- Homo sapiens
- Catalogue number
- 11190
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: Amyloid-beta precursor protein (APP) · Homo sapiens
Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(o) and JIP. Inhibits G(o) alpha ATPase activity.
Subcellular location: Cell membrane; Membrane; Perikaryon; Cell projection, growth cone; Membrane, clathrin-coated pit; Early endosome; Cytoplasmic vesicle
Tissue specificity: Expressed in the brain and in cerebrospinal fluid (at protein level). Expressed in all fetal tissues examined with highest levels in brain, kidney, heart and spleen. Weak expression in liver.
Sequence length: 770 aa · 86943 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il